Study of the possibilities of improving the results of protocols of АRT in patients with poor reproductive prognosis

Authors

  • G. Strelko
  • B. Aydin
  • V. Ulanova
  • O. Malyuta
  • T. Peschanaya
  • N. Korotkevich
  • M. Korobko

Keywords:

controlled ovarian stimulation, corinollitropin-alpha, Ca ionophore, IVF, ICSI

Abstract

Purpose of the study. Study of the effectiveness of the use of Ca ionophore in IVF - ICSI protocols in patients with a poor
reproductive prognosis.
Materials and methods. A study was conducted of the effectiveness of the method of oocyte activation in ECO-ICSI
protocols in patients after at least one unsuccessful attempt of ART. The protocols of controlled ovarian stimulation were
similar in bouth grops. Effectiveness was estimated on the basis of embryological ( fertilization rate, embryo cleavage,
blastulation rate) and clinical indicators (pregnancy rate).
Results. The use of calcium ionophore at the time of the ICSI procedure allows to improve the percentage of oocyte
fertilization, the percentage of cleavage, the percentage of blastulation. This, in turn, has increased the pregnancy rate in the
IVF-ICSI treatment.
Conclusion Improvement of embryological parameters allowed to significantly improve the results of the frequency of
pregnancy in women of older reproductive age with a reduced prognosis for the occurrence of pregnancy.

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Additional Files

Published

2019-07-01

How to Cite

[1]
Strelko Г., Aydin Б., Ulanova В., Malyuta О., Peschanaya Т., Korotkevich Н. and Korobko М. 2019. Study of the possibilities of improving the results of protocols of АRT in patients with poor reproductive prognosis. Reproductive Medicine. 2 (39) (Jul. 2019), 48–52.

Issue

No. 2 (39) (2019): Reproductive medicine

Section

Статьи

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