Application of autologous platelet-rich plasma (APRP) for preparation of the endometrium in art cycles

Authors

  • R.T. Mustafin
  • S.M. Magarmanova
  • T.M. Gerdt
  • G.B. Kaldyigulova

Keywords:

autologous platelet-rich plasma, thin endometrium, in vitro fertilization

Abstract

Despite the fact that PRP-therapy has established itself in many branches of medicine as a safe, reproducible, effective
method of treatment, attempts to use it in reproductology have appeared relatively recently. Analysis of the effectiveness of
IVF cycles using autologous platelet-rich plasma showed that the use of this method helps to improve implantation and can
have a positive effect on the effectiveness of ART programs.

References

Khalifa E, Brzyski RG, Oehninger S, Acosta AA and Muasher SJ. Sonographic appearance of the endometrium: the predictive value for the outcome of in-vitro fertilization in stimulated cycles. Human Reproduction 1992; 7: 677-680.

Chen MJ, Yang JH, Peng FH, Chen SU, Ho HN and Yang YS. Extended estrogen administration for women with thin endometrium in frozen-thawed in-vitro fertilization programs. Journal of assisted reproduction and genetics 2006; 23: 337-342.

Khairy M, Banerjee K, El-Toukhy T, Coomarasamy A and Khalaf Y. Aspirin in women undergoing in vitro fertilization treatment: a systematic review and meta-analysis. Fertility and Sterility 2007; 88: 822-831.

Takasaki A, Tamura H, Miwa I, Taketani T, Shimamura K and Sugino N. Endometrial growth and uterine blood flow: a pilot study for improving endometrial thickness in the patients with a thin endometrium. Fertil Steril 2010; 93: 1851-1858.

Sher G and Fisch JD. Effect of vaginal sildenafil on the outcome of in vitro fertilization (IVF) after multiple IVF failures attributed to poor endometrial development. Fertility and Sterility 2002; 78: 1073-1076.

Ho M, Huang LC, Chang YY, Chen HY, Chang WC, Yang TC and Tsai HD. Electroacupuncture reduces uterine artery blood flow impedance in infertile women. Taiwan J Obstet Gynecol 2009; 48: 148-151.

Scarpellini F., Sbraia M. Use of granulocyte colony-stimulating factor for the treatment of unexplained recurrent miscarriage: a randomised controlled trial. Human Reproduction, 2009; 24;703-708.

Yajie Chang, Jingjie Li, Yuqing Chen, Lina Wei, Xing Yang, Yanan Shi, Xiaoyan Liang. Autologous platelet-rich plasma promotes endometrial growth and improves pregnancy outcome during in vitro fertilization. Int J Clin Exp Med 2015; 8(1):1286-1290

D.M. Obidnyak, A.M. Gzgzyan, D.A. Niauri, I.Z. Chhaidze. Perspektivyi primeneniya autologichnoy obogaschennoy trombotsitami plazmyi krovi u patsientok s povtornyimi neeffektivnyimi popyitkami implantatsii. Problemyi reproduktsii, 5, 2017, 84-88.

Aghajanova L., Houshdaran S., Balayan S., Manvelyan E., Irwin JC., Huddleston HG., Giudice LC. In vitro evidence that platelet-rich plasma stimulates cellular processes involved in endometrial regeneration. Journal of assisted reproduction and genetics 2018 May; 35(5):757-770.

Dhillon RS, Schwarz EM and Maloney MD. Platelet-rich plasma therapy - future or trend? Arthritis Res Ther 2012; 14: 219.

Honinov B.V., Sergunin O.N., Skoroglyadov P.A., Begaliev A.A. Primenenie vnutrisustavnyih in’ektsiy v lechenii osteoartrozov i perspektivyi ispolzovaniya obogaschennoy trombotsitami plazmyi. Vestnik RGMU 2014; 3: 36-40

Additional Files

Published

2019-10-01

How to Cite

[1]
Mustafin Р. , Magarmanova С., Gerdt Т. and Kaldyigulova Г. 2019. Application of autologous platelet-rich plasma (APRP) for preparation of the endometrium in art cycles. Reproductive Medicine. 3 (40) (Oct. 2019), 37–39.