Effectiveness of using the double trigger for final maturation of folicules in the IVF program in women with a reduced ovarial reserve

Authors

  • G.V. Strelko
  • E.A. Nochvina

Keywords:

final oocyte maturation trigger, human chorionic gonadotropin, agonist GnRH, poor responsers

Abstract

PURPOSE OF THE RESEARCH
Research of the effectiveness of the use of the double trigger of HCG + aGnRH in women with a reduced response to stimulation by estimating the number of received oocytes, splitting the embryos, pregnancy and implantation rates.
MATERIALS AND METHODS
Research was conducted on the performance of the use of the double trigger HCG + aGnRH in women – “poor responsers”
in comparison with the introduction of HCH only as a traditional trigger.
RESULTS
By analyzing the results of the proposed stimulation scheme using a double trigger in “bad responsers”, a statistically significant difference in the number of received oocytes, their maturity, embryo transfer frequency and pregnancy rate was proved.
CONCLUSION
It was found that in women with a reduced response to stimulation, the introduction of the double trigger of final follicular
maturation statistically significantly affects the number of oocytes with a relatively high level of MII, which also significantly
increases the pregnancy rate not only due to the generation of more mature oocytes, but also due to the effect on abnormal
endocrine profile, which takes place in this contingent of women.

References

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Additional Files

Published

2019-12-30

How to Cite

[1]
Strelko Г. and Nochvina Е. 2019. Effectiveness of using the double trigger for final maturation of folicules in the IVF program in women with a reduced ovarial reserve. Reproductive Medicine (Central Asia). 4 (41) (Dec. 2019), 33–39.

Issue

No. 4 (41) (2019): Reproductive medicine

Section

Статьи

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