Analysis of the premature birth causes

Authors

  • Sh.M. Saduakasova
  • Zh.U. Bazarbaeva
  • A.N. Aigyrbaeva
  • A.A. Almasbek KazNMU
  • A.B. Kurbanbay
  • D.A. Zholbarys
  • A.Sh. Primbetova
  • A.A. Toleubaeva

DOI:

https://doi.org/10.37800/RM.1.2024.34-43

Keywords:

premature birth, gestational arterial hypertension, placenta previa, prenatal rupture of amniotic fluid, premature rupture of amniotic fluid, induction of labor, genitourinary tract infections

Abstract

Relevance: Premature birth is one of the most pressing problems of modern medicine and is defined as a multifactorial syndrome with many causes and main factors, including complications from the mother or fetus, requiring medical intervention to terminate pregnancy. It is estimated that 11% of all live births in the world are premature, whereas, in women with placenta previa or low-lying placenta, this risk is reported to increase 2-4 times.
The study aimed to assess the role and importance of gynecological diseases to determine the causes and their impact on the risk of premature birth.
Materials and Methods: We examined 66 women of reproductive age. This comparative, prospective study was based on the city polyclinic No. 36 in Almaty and was conducted from January to November 2023. The women included in the study were identified by the International Classification of Diseases (ICD) codes and entered into the Damumed electronic medical documentation system.
Results: The article presents the results of a prospective study of childbirth in pregnant women whose labor was complicated by premature and prenatal outpouring of amniotic fluid. As a result of the analysis of obstetric anamnesis in pregnant women, it was revealed that 20 women (30.3%) were pregnant, and high parity was detected in 18 (27.27%) women. When studying the anamnesis of women with PR in the study, it was found that during previous pregnancies, episodes of bacterial vaginosis were observed in 9 (13.64%) women. During this pregnancy, asymptomatic bacteriuria was diagnosed in 21 (31.82%) cases.
Conclusion: The analysis results revealed A very high correlation between genitourinary tract infections and the risk of premature birth. Both women with placenta previa and those with low-lying placenta have an increased risk of premature birth. This increased risk is the same for all degrees of severity of premature birth. Concomitant risk factors for premature birth were the advanced age of the mother, secondhand smoke, hypertension, a history of abortions, and premature rupture of the membranes.

References

Ornaghi S, Vaglio Tessitore I, Vergani P. Pregnancy and Delivery Outcomes in Women With Persistent Versus Resolved Low-Lying Placenta in the Late Third Trimester. Journal of Ultrasound Medicine. 2022;41:123-133.

https://doi.org/10.1002/jum.15687

Кабыл Б., Исенова С., Нурланова Г., Бурибаева Ж., Адилова К., Аязбай К., Толенова Ж., Махамбет А. Предикторы и факторы риска спонтанных преждевременных родов: анамнестические характеристики, ультразвуковые и биомаркеры (обзор литерату-

ры). Репродуктивная медицина. 2023;3(56):63-71.

Kabyl B, Isenova S, Nurlanova G, Buribaeva Zh, Adilova K, Ajazbaj K, Tolenova Zh, Mahambet A. Predictors and risk factors of spontaneous premature birth: Аnamnestic characteristics, ultrasound, and biomarkers (a literature review). Reproduktivnaja medicina. 2023; 3(56): 63-71. (In Russ.).

https://doi.org/10.37800/RM.3.2023.63-71

Salim NA, Satti I. Risk factors of placenta previa with maternal and neonatal outcome at Dongola/Sudan. Journal of Family Medicine and Primary Care. 2021;10(3):1215-1217.

https://doi.org/10.4103/jfmpc.jfmpc_2111_20

Patel RM. Short- and long-term outcomes for extremely preterm infants. American Journal of Perinatology. 2016;33(3):318-328. https://doi.org/10.1055/s-0035-1571202

Stensvold HJ, Klingenberg C, Stoen R, Moster D, Braekke K, Guthe HJ. Neonatal morbidity and 1-year survival of extremely preterm infants. Pediatrics. 2017;139(3):e20161821.

https://doi.org/10.1542/peds.2016-1821

Исенова С.Ш., Казыбаева А.С., Божбанбаева Н.С., Асемов А., Баймусанова Г.Н., Кабыл Б.К., Исина Г.М. Преждеврменные роды и Streptococcus группы Б. – есть ли связь? (обзор литературы). Репродуктивная медицина. 2022;4(53):47-54.

Isenova SSh, Kazybaeva AS, Bozhbanbaeva NS, Asemov A, Bajmusanova GN, Kabyl BK, Isina GM. Premature labor and group B Streptococcus – is there a link? (A literature review). Reproduktivnaja medicina. 2022;4(53):47-54. (In Russ.) https://doi.org/10.37800/RM.3.2022.47-54

Wortman AC, Twickler DM, McIntire DD, Dashe JS. Bleeding complications in pregnancies with low-lying placenta. Journal of Maternal, Fetal & Neonatal Medicine. 2016;29(9):1367-1371.

https://doi.org/10.3109/14767058.2015.1051023

King LJ, Dhanya Mackeen A, Nordberg C, Paglia MJ. Maternal risk factors associated with persistent placenta previa. Placenta. 2020;99:189-192.

https://doi.org/10.1016/j.placenta.2020.08.004

Lucaroni F. Biomarkers for predicting spontaneous preterm birth: An umbrella systematic review. Journal of Maternal, Fetal & Neonatal Medicine. 2018;31:726-734.

https://doi.org/10.1080/14767058.2017.1297404

Long SY, Yang Q, Chi R, Luo L, Xiong X, Chen ZQ. Maternal and neonatal outcomes resulting from antepartum hemorrhage in women with placenta previa and its associated risk factors: A single-center retrospective study. Therapeutics and Clinical Risk Management. 2021;17:31-38.

https://doi.org/10.2147/tcrm.s288461

Taga A, Sato Y, Sakae C, Satake Y, Emoto I, Maruyama S. Planned vaginal delivery versus planned cesarean delivery in cases of low-lying placenta. Journal of Maternal, Fetal & Neonatal Medicine. 2017;30(5):618-622.

https://doi.org/10.1080/14767058.2016.1181168

Kothapalli D, Kolluru K. Placenta previa and its effect on maternal and fetal outcome; a retrospective observational study. International Journal of Reproduction, Contraception, Obstetrics & Gynecology. 2021;10:2720-2724.

https://doi.org/10.18203/2320-1770.ijrcog20212656

Abdel-Aleem H, Shaaban OM, Abdel-Aleem MA, Aboelfadle MA. Cervical pessary for preventing preterm birth in singleton

pregnancies. Cochrane Database Systematic Reviews. 2022;12(12):CD014508.

https://www.cochranelibrary.com/cdsr/doi/10.1002/14651858.CD014508/full

Alfirevic Z, Stampalija T, Medley N. Cervical stitch (cerclage) for preventing preterm birth in singleton pregnancy. Cochrane Database

Systematic Reviews. 2017;6:CD008991.

https://doi.org/10.1002/14651858.cd008991.pub3

Puertas A, Magan-Fernandez A, Blanc V, Revelles L, O’Valle F, Pozo E. Association of periodontitis with preterm birth and low birth weight: a comprehensive review. Journal of Maternal & Neonatal Medicine. 2018;31(5):597-602. https://doi.org/10.1080/14767058.2017.1293023

Londero AP, Rossetti E, Pittini C, Cagnacci A, Driul L. Maternal age and the risk of adverse pregnancy outcomes: a retrospective cohort study. BMC Pregnancy & Childbirth. 2019;19(1):261.

https://doi.org/10.1186/s12884-019-2400-x

Gabor M, Kunochova I, Krizko M, Alfoldi M, Feriancova M, Ferianec V. Simple ultrasound evaluation of fetal adrenal glands as a marker of imminent preterm birth: a preliminary report. Bratisl Lek Listy. 2021;10(122):721-726. https://pubmed.ncbi.nlm.nih.gov/34570573/

Sadeghi M, Kahouei M, Pahlevanynejad S, Valinejadi A, Momeni M, Kermani F, Seddighi H. Mobile applications for prematurity: a systematic review protocol. BMJ Paediatr Open. 2021;5(1):e001183.

http://dx.doi.org/10.1136/bmjpo-2021-001183

Vogel JP, Chawanpaiboon S, Moller AB, Watananirun K, Bonet M, Lumbiganon P. The global epidemiology of preterm birth. Best Practice & Research Clinical Obstetrics & Gynaecology. 2018;52:3-12.

https://doi.org/10.1016/j.bpobgyn.2018.04.003

Ахильгова З.С. Заболевания пародонта и преждевременные роды (обзор литературы). Вестник новых медицинских технологий [Интернет]. 2018;1:159-165

Ahil'gova ZS. Periodontal diseases and premature birth (A literature review). Vestnik novyh medicinskih tehnologij [Intenet]. 2018;1:159-165. (In Russ.)

https://cyberleninka.ru/article/n/zabolevaniya-parodonta-i-prezhdevremennye-rody-obzor-literatury

Published

2024-04-01

How to Cite

[1]
Saduakasova Ш. , Bazarbaeva Ж. , Aigyrbaeva А. , Buzumova Ж. , Almasbek А. , Kurbanbay А., Zholbarys Д. , Primbetova А. and Toleubaeva А. 2024. Analysis of the premature birth causes. Reproductive Medicine. 1 (Apr. 2024), 34–43. DOI:https://doi.org/10.37800/RM.1.2024.34-43.

Issue

Section

Статьи