Features of pregnancy course and outcomes in women with severe COVID-19
DOI:
https://doi.org/10.37800/RM.1.2024.52-59Keywords:
viral pneumonia, coronavirus infection, COVID-19, pregnancy, SARS-CoVAbstract
Relevance: In 2019, the country registered 10,259 pregnant women infected with COVID-19 and suffering from pneumonia, accounting for 5% of the total. Of these, 29% of women were in severe condition (2975), 99.2% (10176) recovered, and 0.8% died.
Note that, according to the World Health Organization (WHO), pregnant women infected with the COVID-19 coronavirus are more likely to experience serious complications requiring hospitalization and mechanical ventilation. The probability of an increase in maternal mortality ranged from 8.3% to 38.6% (12,190 and 56,700 cases) in 118 countries.
The study aimed to study the clinical picture and course of COVID-19 in pregnant women to predict the severity of the disease and the course and outcome of pregnancy.
Materials and methods: The method chosen for the study was a retrospective epidemiological case-control study (from April 2020 to May 2022). The leading group consisted of 60 pregnant women with COVID-19 and a comparison group of 60 with viral pneumonia not confirmed by COVID-19.
Results: The following conclusions were drawn: pregnant women with COVID-19 are at risk of preterm birth regardless of disease severity in the second and third trimesters; characteristic complications of pregnancy often occur in the third trimester of pregnancy and are manifested by premature rupture of amniotic fluid; a large number of complications in the postpartum period were observed in women in labor who had COVID-19 in the acute phase.
Conclusion: The most important factors for the severe course of COVID-19 in pregnant women who have suffered serious conditions are the lack of preventive measures, concomitant respiratory diseases, the presence of sexually transmitted infections, and obesity.
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