Assisted Reproductive Technologies in Kazakhstan (2020 National ART Registry data)
DOI:
https://doi.org/10.37800/RM.1.2024.8-16Keywords:
assisted reproductive technologies (ART), 2020 ART report, IVF, ART accessibilityAbstract
Relevance: The article presents aggregate data on the programs of assisted reproductive technologies (ART) implemented in 2020 in Kazakhstani clinics specializing in treating infertility using ART.
The study aimed to analyze the structure and results of ART cycles conducted and Registered in the Republic of Kazakhstan from 1 January 2020 to 31 December 2020.
Materials and Methods: A retrospective analysis of data from reports of 17 ART clinics in Kazakhstan, which were voluntarily submitted to the Kazakhstan Association of Reproductive Medicine (KARM), was conducted. The reports included information on IVF cycles, ICSI, embryo cryopreservation, oocyte donation (OD), surrogacy, and preimplantation genetic testing (PGT).
Results: The total number of ART cycles available for analysis in 2020 was 17,743, resulting in the birth of 5,932 newborns. The accessibility of ART treatment amounted to 952 cycles per 1 million population.
Analysis of the ART structure revealed that IVF cycles accounted for 11.9% of all ART cycles in clinics in Kazakhstan, while ICSI was 33.4%.
A combined method of fertilization, using both IVF and ICSI (50/50), was performed in 13.0% of cycles. Frozen embryo transfer (FET) was conducted in 47.4% of cycles, while OD programs were carried out in 11.4% of cycles and PGT in 5.3% of cycles.
The pregnancy rate per aspiration in 2020 was 20.9% for IVF cycles, 20.4% for ICSI cycles, and 42.5% for FET cycles. When calculated per transfer, the pregnancy rate was 38.5% for IVF cycles and 39.5% for ICSI cycles. For OD programs, the pregnancy rate per aspiration was 50.6%. In 2020, live birth rates were 30.7% in fresh IVF cycles, 32.4% in ICSI cycles, 33.4% in FET cycles, and 42.0% in OD programs.
In 2020, 1,103 programs were conducted in Kazakhstan. The Registry of pregnant women and women of fertile age reported the pregnancy rate of 46%, the live birth rate of 26%, and the frequency of multiple births of 21.8%.
Conclusion: According to the Registry, the number of ART programs increased by 1.1% in 2020 vs. the previous year. The negative impact of COVID-19 on this indicator is unquestionable. The pregnancy and live birth rates remained stable and corresponded to the average ESHRE indicators.
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