Vitamin D and habitual missarriage: A case-control study
DOI:
https://doi.org/10.37800/RM.1.2025.454Keywords:
habitual miscarriage, spontaneous abortion, Vitamin D, women of reproductive ageAbstract
Relevance: Vitamin D plays an important role in a woman’s reproductive health, and its deficiency may be among the factors that lead to habitual miscarriage. Vitamin D is not just a vitamin but rather a hormone that plays a key role in many body processes. In addition to the traditionally known role in strengthening bone tissue, it is actively involved in a wide variety of body processes, from the functioning of the nervous system to maintaining immunity and reproductive function.
The study aimed to assess the level of vitamin D in women with recurrent miscarriage in comparison with healthy women to identify possible pathophysiological relationships and determine its role in reproductive health.
Methods: The study involved 130 women who were divided into two groups. The case group included 65 women with two or more spontaneous miscarriages or a non-developing pregnancy before 22 weeks of gestational age, and the control group included 65 women with a history of two or more normal births.
Results: This study revealed inadequate vitamin levels in both groups. Vitamin D levels were below the reference values in women at risk of miscarriage but still higher than in women without miscarriage who were deficient in vitamin D.
Conclusion: The study results showed that low vitamin D levels can increase the risk of spontaneous abortion in both women with habitual miscarriage and healthy women.
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