Reasons for endometriosis-associated infertility
DOI:
https://doi.org/10.37800/RM2020-1-17Keywords:
endometriosis, infertilityAbstract
This article discusses the causes and mechanisms of the occurrence of infertility in endometriosis within the framework of versions and contraversions. The magnitude of the described problem is noted not only from a medical, but also from a socio-economic perspective. Four main factors of endometriosis-associated infertility were identified: tubal-peritoneal, ovarian,
embryonic and endometrial. Given the inconsistency of scientific data, the need for further research is noted.
References
How old is endometriosis? Late 17th and 18th century description of the disease. Fertil Steril. 1999; 72: 10-4.
Стрижаков А.Н. Современные аспекты этиологии и патогенеза различных форм генитального эндометриоза. Акушерство и гинекология. 1980; 10:13–17 [Strizhakov A.N. Sovremennye aspekty etiologii i patogeneza razlichnyh form genital'nogo endometrioza. Akusherstvo i ginekologiya. 1980; 10:13–17 (In Russian)].
Sun TT, Chen SK, Li XY et al. Fertility Outcomes After Laparoscopic Cystectomy in Infertile Patients with Stage III-IV Endometriosis: a Cohort with 6-10 years of Follow-up. Adv Ther. 2020. https://doi.org/10.6084/m9.figshare.11968545.
Santulli P, Lamau MC, Marcellin L et al. Endometriosis-related infertility: ovarian endometrioma per se is not associated with presentation for infertility. Hum Reprod. 2016; 31(8): 1765-75.
Ahn SH, Monsanto SP, Miller C et al. Pathophysiology and immune dysfunction in endometriosis. Biomed Res Int. 2015; 2015: 795976.
Nanda A, K T, Banerjee P, Dutta M et al. Cytokines, Angiogenesis, and Extracellular Matrix Degradation are Augmented by Oxidative Stress in Endometriosis. Ann Lab Med. 2020; 40(5): 390-397.
Адамян Л.В., Мартиросян Я.О., Асатурова А.В. Этиопатогенез эндометриоз-ассоциированного бесплодия (обзор литературы). Проблемы репродукции. 2018; 24(2): 28-33. [Adamyan L.V., Martirosyan YA.O., Asaturova A.V. Etiopatogenez endometrioz-associirovannogo besplodiya (obzor literatury). Problemy reprodukcii. 2018; 24(2): 28-33 (In Russian)].
Khan KN, Fujishita A, Hiraki K et al. Bacterial contamination hypothesis: a new concept in endometriosis. Reprod Med Biol. 2018;17(2):125-133.
Akira S., Takeda K. Toll-like receptor signaling. Nat Rev Immunol. 2004; 4: 499–511.
Оразов М.Р. Токтар Л.Р. Бактериальная контаминация: новое слово в патогенезе эндометриоза. Акушерство и гинекология: новости, мнения, обучение. 2018; 6(3): 29–37. [Orazov M.R. Toktar L.R. Bakterial'naya kontaminaciya: novoe slovo v patogeneze endometrioza. Akusherstvo i ginekologiya: novosti, mneniya, obuchenie. 2018; 6(3): 29–37 (In Russian)].
Kitajima M., Dolmans M.-M., Donnez O. et al. Enhanced follicular recruitment and atresia in cortex derived from ovaries with endometriomas. Fertil. Steril. 2014; 101: 1031–1037.
Jwabuchi T, Yoshimoto C, Shigetomi H, Kobayashi H. Oxidative stress and antioxidant defense in endometriosis and its malignant transformation. Oxid Med Cell Longev. 2015; 2015: 848595.
Wu G., Bersinger N., Mueller M., Von Wolff M. et al Intrafollicular inflammatory cytokines but not steroid hormone concentrations are increased in naturally matured follicles of women with proven endometriosis. Journal of assisted reproduction and genetics. 2017; 34: 357-364
Singh AK, Dutta M, Chattopadhyay R et al. Intrafollicular interleukin-8, interleukin-12, and adrenomedullin are the promising prognostic markers of oocyte and embryo quality in women with endometriosis. J. Assist. Reprod. Genet. 2016; 33: 1363–1372.
Yland J, Carvalho LFP, Beste M et al. Endometrioma, the follicular fluid inflammatory network and its association with oocyte and embryo characteristics. Reprod Biomed Online. 2020; 40(3): 399-408.
RCOG. The Effect of Surgery for Endometriomas on Fertility: Scientific Impact Paper No. 55. BJOG. 2018; 125: e19-e28.
Hamdan M, Dunselman G, Li TC et al. The impact of endometrioma on IVF/ICSI outcomes: a systematic review and metaanalysis. Hum Reprod Update. 2015; 21: 809–825.
Muzii L, Di Tucci C, Di Feliciantonio M et al. Antimullerian hormone is reduced in the presence of ovarian endometriomas: a systematic review and meta-analysis. Fertil Steril. 2018; 110: 932–940.:e931.
Streuli I, de Ziegler D, Gayet V et al. In women with endometriosis anti-Müllerian hormone levels are decreased only in those with previous endometrioma surgery. Hum Reprod. 2012; 27(11): 3294-303.
Yılmaz Hanege B, Güler Çekıç S, Ata B. Endometrioma and ovarian reserve: effects of endometriomata per se and its surgical treatment on the ovarian reserve. Facts Views Vis Obgyn. 2019; 11(2): 151-157.
Kucera R, Babuska V, Ulcova-Gallova Z, Kulda V, Topolcan O. Follicular fluid levels of anti-Müllerian hormone, insulinlike growth factor 1 and leptin in women with fertility disorders. Syst Biol Reprod Med. 2018; 64: 220–223.
Freis A., Dietrich J.E., Binder M. et al. Relative Morphokinetics Assessed by Time-Lapse Imaging Are Altered in Embryos From Patients With Endometriosis. Reprod. Sci. 2018; 25: 1279–1285.
Juneau C, Kraus E, Werner M et al. Patients with endometriosis have aneuploidy rates to their age-matched peers in the in vitro fertilization population. Fertil Steril. 2017; 108: 284–8.
Máté G, Bernstein LR, Török AL. Endometriosis Is a Cause of Infertility. Does Reactive Oxygen Damage to Gametes and Embryos Play a Key Role in the Pathogenesis of Infertility Caused by Endometriosis? Front Endocrinol (Lausanne). 2018; 9: 725.
Da Broi MG, Jordão AA, Ferriani RA, Navarro PA. Oocyte oxidative DNA damage may be involved in minimal/mild endometriosis-related infertility. Mol Reprod Dev. 2018; 85: 128–36.
Sanchez AM, Pagliardini L, Cermisoni GC et al. Does Endometriosis Influence the Embryo Quality and/or Development? Insights from a Large Retrospective Matched Cohort Study. Diagnostics (Basel). 2020; 10(2). pii: E83.
М.Р. Оразов, М.Б. Хамошина, Л.М. Михалева и др. Молекулярно-генетические особенности состояния эндометрия при эндометриоз-ассоциированном бесплодии. Трудный пациент. 2020; 1(18): 23-32. [M.R. Orazov, M.B. Hamoshina, L.M. Mihaleva i dr. Molekulyarno-geneticheskie osobennosti sostoyaniya endometriya pri endometrioz-associirovannom besplodii. Trudnyj pacient. 2020; 1(18): 23-32. (in Russian)].
Lessey BA, Lebovic DI, Taylor RN. Eutopic endometrium in women with endometriosis: ground zero for the study of implantation defects. Seminars in reproductive medicine. 2013; 31: 109–24.
Lessey BA, Young SL. Homeostasis imbalance in the endometrium of women with implantation defects: the role of estrogen and progesterone. Seminars in reproductive medicine. 2014; 32: 365–75.
Lessey BA, Kim JJ. Endometrial Receptivity in Eutopic Endometrium of Women with Endometriosis It is affected, let me show you why. Fertil Steril. 2017; 108(1): 19–27.
Sung L, Mukherjee T, Takeshige T, Bustillo M, Copperman AB. Endometriosis is not detrimental to embryo implantation in oocyte recipients. J Assist Reprod Genet 1997; 14: 152–6.
Simon C, Gutierrez A, Vidal A, de los Santos MJ, Tarín JJ, Remohí J, et al. Outcome of patients with endometriosis in assisted reproduction: results from in-vitro fertilization and oocyte donation. Hum Reprod 1994; 9: 725–9.
Díaz I, Navarro J, Blasco L, Simon C, Pellicer A, Remohí J. Impact of stage III – IV endometriosis on recipients of sibling oocytes: matched case-control study. Fertil Steril 2000; 74: 31–4.
Miravet-Valenciano J, Ruiz-Alonso M, Gomez E, Garcia-Velasco JA. Endometrial receptivity in eutopic endometrium in patients with endometriosis: it is not affected, and let me show you why. Fertil Steril. 2017; 108: 28–31.
Díaz-Gimeno P, Horcajadas JA, Martínez-Conejero JA, Esteban FJ, Alama P, Pellicer A, et al. A genomic diagnostic tool for human endometrial receptivity based on the transcriptomic signature. Fertil Steril 2011; 95: 50–60.
Garcia-Velasco JA, Fassbender A, Ruiz-Alonso M, Blesa D, Thomas DH, Simon C. Is endometrial receptivity transcriptomics affected in women with endometriosis? A pilot study. Reprod Biomed Online 2015; 31: 647–54
Craciunas L, Gallos I, Chu J et al. Conventional and modern markers of endometrial receptivity: a systematic review and meta-analysis. Hum Reprod Update. 2019; 25(2): 202-223.
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