ROSI technology: injection of haploid round spermatids
DOI:
https://doi.org/10.37800/RM.4.2021.43-47Keywords:
nonobstructive azoospermia, male infertility, round spermatid injection, round spermatids, ROSIAbstract
Relevance: According to micro-testicular sperm extraction (Micro-TESE) results, many azoospermic men have no mature spermatozoa but possess haploid round spermatids that can be injected into oocytes and lead to fertilization.
The purpose was a systematic review of articles on round spermatid injection technique (ROSI).
Methods: Articles on ROSI were searched in medical databases like PUBMED, MEDLINE, and EMBASE by the keywords “round spermatid injection” and “ROSI.”
Results: The article offers a review of several successful and unsuccessful cases of using the ROSI technique.
Conclusion: According to our review, the ROSI technique can serve as a last resort for men with non-obstructive azoospermia eager to use their genetic material to procreate.
References
Cocuzza M., Alvarenga C., Pagani R. The epidemiology and etiology of azoospermia // Clinics (Sao Paulo). – 2013. – Vol. 68 Suppl 1(Suppl 1). – P. 15-26. https://doi.org/10.6061/clinics/2013(sup01)03;
Gross K.X., Hanson B.M., Hotaling J.M. Round Spermatid Injection // Urol. Clin. North Am. – 2020. – Vol. 47(2). – P. 175-183. https://doi.org/10.1016/j.ucl.2019.12.004;
Tekayev M., Vuruskan A.K. Clinical values and advances in round spermatid injection (ROSI) // Reprod. Biol. – 2021. – Vol. 21(3). – No. 100530. https://doi.org/10.1016/j.repbio.2021.100530;
Tanaka A., Nagayoshi M., Takemoto Y., Tanaka I., Kusunoki H., Watanabe S., Kuroda K., Takeda S., Ito M., Yanagimachi R. Fourteen babies born after round spermatid injection into human oocytes // Proc. Natl. Acad. Sci. USA. – 2015. – Vol. 112(47). – P. 14629-14634. https://doi.org/10.1073/pnas.1517466112;
Edwards R.G., Tarin J.J., Dean N., Hirsch A., Tan S.L. Are spermatid injections into human oocytes now mandatory? // Hum. Reprod. – 1994. – Vol. 9(12). – P. 2217-2219. https://doi.org/10.1093/oxfordjournals.humrep.a138426;
Kerr J.B., Loveland K.A.L., O’Bryan M.K., de Kretser D.M. Cytology of the testis and intrinsic control mechanisms // In: J.D. Neill, J.R.G. Challis, D.M. de Kretser, D.W. Pfaff, J.S. Richards, T.M. Plant, P.M. Wassarman (Eds.). Knobil and Neill’s Physiology of Reproduction. –3 ed. – Elsevier, 2006. – P. 827 - 947;
Tanaka A., Suzuki K., Nagayoshi M., Tanaka A., Takemoto Y., Watanabe S., Takeda S., Irahara M., Kuji N., Yamagata Z., Yanagimachi R. Ninety babies born after round spermatid injection into oocytes: survey of their development from fertilization to 2 years of age // Fertil Steril. – 2018. – Vol. 110(3). – P. 443-451. https://doi.org/10.1016/j.fertnstert.2018.04.033;
Hanson B.M., Kohn T.P., Pastuszak A.W., Scott R.T. Jr., Cheng P.J., Hotaling J.M. Round spermatid injection into human oocytes: a systematic review and meta-analysis // Asian J. Androl. – 2021. – Vol. 23(4). – P. 363-369. https://doi.org/10.4103/ aja.aja_85_20;
Amdani S.N., Jones C., Coward K. Phospholipase C zeta (PLCζ): oocyte activation and clinical links to male factor infertility // Adv. Biol. Regul. – 2013. – Vol. 53(3). – P. 292-308. https://doi.org/10.1016/j.jbior.2013.07.005;
Kashir J., Heindryckx B., Jones C., De Sutter P., Parrington J., Coward K. Oocyte activation, phospholipase C zeta and human infertility // Hum. Reprod. Update. – 2010. – Vol. 16(6). – P. 690-703. https://doi.org/10.1093/humupd/dmq018;
Ramadan W.M., Kashir J., Jones C., Coward K. Oocyte activation and phospholipase C zeta (PLCζ): diagnostic and therapeutic implications for assisted reproductive technology // Cell Commun. Signal. – 2012. – Vol. 10(1). – No. 12. https:// doi.org/10.1186/1478-811X-10-12.
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