Features of pregnancy course and management after in vitro fertilization

Authors

  • S.Sh. Isenova
  • N.A. Tileukul Казахский национальный медицинский университет им. С.Д. Асфендиярова
  • A.S. Aripkhanova
  • A.M. Boran
  • N.O. Makulbekova

DOI:

https://doi.org/10.37800/RM.2.2023.17-24

Keywords:

in vitro fertilization (IVF), Infertility, additional reproductive technologies (ART), placenta previa, progesterone support, premature birth, thrombophilia

Abstract

Relevance: Infertility is a global public health problem. The prevalence of infertile marriages in the world is 12-15%,
including 10.9% in Western Europe, 14.2% in the US, 17.4% in Russia, and 15% in Kazakhstan, and there is no downward trend. Every year 2-2.5 million new cases of male and female infertility are registered worldwide. IVF can predispose the mother to increased risks and complications during pregnancy. The European Society for Human Reproduction and Embryology (ESHRE) reports that the most important indicator of the success of ART treatment is the birth of one healthy child.
The study aimed to study the features of the course of pregnancy and aspects of antenatal follow-up after IVF.
Materials and methods: With PubMed, Medline, Cochrane Library, LILACS, WHO, Scopus, and Web of Science, a
literature review has been done over five years. The International Center for Clinical Reproductology “PERSONA” conducted a retrospective analysis of the records of the history of childbirth of 450 women after IVF who were registered for pregnancy from 9 weeks. Pregnant women were selected from 2018 to 2022 using a simple random sampling method. Group 1 (N=300) – single-fetal pregnancy after IVF. Group 2 (N=150) - spontaneous single-fetal pregnancy.
Results: In the main group were significantly more common: thrombophilia of various genesis (8% vs. 3%), chronic arterial hypertension (27% vs. 13%), and isthmic-cervical insufficiency, and therefore surgical correction of the cervix was performed (33%). In the IVF group, in 80% of cases, long-term progesterone support was carried out. The main group used antiviral and antibacterial drugs twice more often.
Conclusion: Pregnant women after IVF are a special group of patients with a particularly burdened obstetric and gynecological history. Pregnant women with a history of infertility and after IVF should be classified as a high-risk group for the development of pregnancy complications such as low placentation, hypertensive conditions, isthmic-cervical insufficiency, and premature birth.

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Published

2023-05-29

How to Cite

[1]
Isenova С., Tileukul Н. , Aripkhanova А., Boran А. and Makulbekova Н. 2023. Features of pregnancy course and management after in vitro fertilization. Reproductive Medicine. 2 (55) (May 2023), 17–24. DOI:https://doi.org/10.37800/RM.2.2023.17-24.

Issue

No. 2 (55) (2023): Reproductive medicine

Section

Статьи

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