Features of the effect of polycystic ovary syndrome on the psychosomatic state of women
DOI:
https://doi.org/10.37800/RM.1.2024.67-73Keywords:
polycystic ovary syndrome, pregnancy, infertility, endometrial hyperplasia, obesity, insulin resistance, cardiovascular complications, miscarriagesAbstract
Relevance: Polycystic ovarian syndrome (PCOS) is a complex reproductive and metabolic disease affecting various aspects of fertility. Most women of fertile age with PCOS are diagnosed with obesity, which exacerbates the clinical manifestations of PCOS, accelerates its manifestation, and significantly contributes to the development of complications. It is known that in patients with obesity in combination with PCOS, arterial hypertension and metabolic disorders are statistically significantly more often detected: dyslipidemia, visceral obesity, insulin resistance, hyperinsulinemia, and hyperuricemia, which collectively increase cardiovascular risk. The factors influencing the course of polycystic ovary syndrome are still the subject of research.
The study aimed to study the peculiarities of the effect of PCOS on the psychosomatic state of women, the relationship of PCOS with obesity, endometrial hyperplasia, pregnancy outcomes, and cardiovascular risks.
Materials and Methods: As part of the study of literary data, a review of scientific studies published in the Cochrane, CyberLeninka, and PubMed databases was conducted. The search depth is 10 years (2013-2023). We studied 116 articles, of which 15 full-text articles were included, and 101 were excluded. The criteria for inclusion of articles were that full-text articles, search queries, and search depth met the requirements. The criteria for exclusion of articles were unrelated to the research topic, duplicate publications, and not matching search queries.
Results: This literature review provides information that PCOS acts as a risk factor for infertility, androgen-dependent dermopathy, disorders of carbohydrate metabolism, including type 2 diabetes mellitus, dyslipidemia, cardiovascular pathology, a high level of spontaneous abortions, endometrial hyperplastic processes, disorders of psychological status – depression, anxiety disorders; oncological diseases.
Conclusion: Women of fertile age with PCOS have a higher risk of infertility and cardiometabolic risk factors, which are compounded by a greater prevalence of overweight and obesity. Women with PCOS are at higher risk of complications during pregnancy and childbirth, which are exacerbated by pre-conception obesity, hyperandrogenism, and possibly higher weight gain during pregnancy.
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