Features of diagnosis and treatment of reproductive health of women with epilepsy: A literature review
DOI:
https://doi.org/10.37800/RM.2.2024.%2045-53Keywords:
epilepsy, women, reproductive health, hormonal influences, antiepileptic drugs, pregnancy and epilepsy, partial and generalized seizuresAbstract
Relevance: Epilepsy in women presents a complex medical problem affecting various aspects of the reproductive cycle, including sexual development, pregnancy, breastfeeding, and menopause.
The study aimed to assess the impact of epilepsy and antiepileptic drugs on reproductive health, sexual function, and the mental state of women, as well as developing recommendations to optimize treatment and improve the quality of life of women with epilepsy.
Materials and Methods: A systematic review of scientific literature was conducted to achieve this goal, including analyzing articles published in peer-reviewed medical journals. The main focus was on studies related to catamenial epilepsy, reproductive and sexual dysfunction, psychiatric disorders, and their relationship with the use of antiepileptic drugs. Content analysis methods were used to identify key aspects and trends in this field.
Results: As a result of the systematic review, it was found that epilepsy in women significantly affects various aspects of their reproductive and mental health. Studies also showed that polycystic ovary syndrome is more common in women taking valproate, highlighting the need for careful selection of antiepileptic drugs. It was established that pregnancy in women with epilepsy requires careful monitoring of antiepileptic drug levels and dose minimization to ensure the safety of both the mother and the fetus. Psychiatric disorders such as depression and anxiety are common comorbid conditions that require special attention during treatment.
Conclusion: This review may interest clinicians, patients, and researchers seeking to improve the treatment outcomes in women of reproductive age with epilepsy and their quality of life. Epilepsy in women requires a comprehensive and individual approach to treatment, taking into account reproductive and hormonal changes. In the therapeutic and diagnostic process, patients’ education and active participation are of particular importance in making decisions about treatment and consulting and monitoring their condition before conception in different phases of life. This approach helps to improve the health and quality of life of women with epilepsy.
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