COVID-19 и женская репродуктивная функция: обзор долгосрочных эффектов, нарушений и клинических подходов к восстановлению
DOI:
https://doi.org/10.37800/RM.4.2025.640Ключевые слова:
COVID-19, SARS-CoV-2, репродуктивное здоровье, овариальный резерв, эндометрий, менструальный цикл, беременностьАннотация
Актуальность: Последствия COVID-19 для репродуктивного здоровья женщин остаются недостаточно изученными, несмотря на растущее количество публикаций о влиянии SARS-CoV-2 на гормональную регуляцию, овариальный резерв и структурное состояние органов малого таза.
Цель исследования – обобщить, систематизировать и критически проанализировать современные данные о долгосрочном влиянии COVID-19 на репродуктивную функцию женщин, включая гормональные, структурные и функциональные изменения.
Материалы и методы: Проведён обзор литературы в базах PubMed, Scopus и Embase (2020-2025), включавший рецензируемые исследования, посвящённые менструальной функции, овариальному резерву, эндометрию, течению беременности и предполагаемым механизмам нарушений.
Результаты: У женщин после COVID-19 выявляются нарушения менструального цикла, снижение АМГ, эндокринные дисфункции, признаки оофорита и изменения эндометрия; у беременных повышены риски осложнений и нарушений плацентации.
Заключение: COVID-19 оказывает комплексное влияние на репродуктивную систему женщин, что требует разработки алгоритмов наблюдения и дальнейших проспективных исследований.
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Copyright (c) 2025 С.Е. Еркенова, В.Н. Локшин, Ш.М. Мойынбаева, А.Э. Миреева, Г.Ж. Кошкимбаева, Л.А. Нурсейтова, А.Р. Толенбекова
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