Mode of delivery and postpartum depression: A systematic review of the literature
DOI:
https://doi.org/10.37800/RM.3.2026.813Keywords:
postpartum depression, mode of delivery, cesarean section, vaginal delivery, psycho-emotional status, systematic reviewAbstract
Relevance: Pregnancy, childbirth, and the early postpartum period are associated with considerable physiological and emotional stress and may lead to psychological changes, including postpartum depression (PPD). Women experiencing PPD may face cognitive, emotional, and somatic problems that significantly affect maternal adaptation and the quality of childcare. The influence of the mode of delivery on the onset and development of PPD remains a subject of scientific interest.
The study aimed to analyze the severity of postpartum depression in women with different modes of delivery and to determine significant differences between vaginal delivery and cesarean section.
Materials and Methods: We conducted a systematic search in the PubMed, Scopus, Web of Science, and Cochrane Library databases using the study keywords. Eligible sources included full-text articles published between 2019 and 2024 in peer-reviewed scientific journals in English or Russian that compared vaginal delivery with cesarean section.
Results: Early PPD most commonly develops within the first 2 weeks after childbirth, whereas late PPD occurs after 6 weeks. In some cases, PPD may persist for up to one year after childbirth. Major contributing factors may include complicated labor, hormonal changes, and lack of social support. The systematic analysis of publications showed that women who delivered by cesarean section had a higher risk of developing PPD, while negative birth experiences, postoperative pain, and lactation problems played a key role. Social and demographic factors also influenced the risk of PPD.
Conclusion: The mode of delivery influences the development of PPD. Operative delivery may negatively affect the occurrence of PPD, whereas uncomplicated vaginal delivery may reduce the risk of developing PPD. The findings emphasize the need for a comprehensive approach that includes perinatal psychological support, individual risk assessment, information about pain management methods, and evidence-based planning of cesarean section.
References
1. Khamidullina Z, Marat A, Muratbekova S, Mustapayeva NM, Chingayeva GN, Shepetov AM, Ibatova SS, Terzic M, Aimagambetova G. Postpartum Depression Epidemiology, Risk Factors, Diagnosis, and Management: An Appraisal of the Current Knowledge and Future Perspectives. J Clin Med. 2025;14(7):2418.
https://doi.org/10.3390/jcm14072418
2. Suryawanshi O, Pajai S. A Comprehensive Review on Postpartum Depression. Cureus. 2023;15(1). Epub 2022.
https://doi.org/10.7759/cureus.32745
3. Горьковая ИА, Александрович ЮС, Микляева АВ, Рязанова ОВ, Коргожа МА. Психопрофилактика послеродовой депрессии у женщин с различными вариантами родоразрешения. Вестник Удмуртского университета. Серия Философия. Психология. Педагогика. 2017;27(4):437-441.
Gorkovaya IA, Aleksandrovich YuS, Miklyaeva AV, Ryazanova OV, Korgozha MA. Psychoprophylaxis of postpartum depression in women with different modes of delivery. Vestnik Udmurtskogo universiteta. Seriya Filosofiya. Psikhologiya. Pedagogika. 2017;27(4):437-441. Russian.
4. Agrawal I, Mehendale AM, Malhotra R. Risk Factors of Postpartum Depression. Cureus. 2022;14(12).
https://doi.org/10.7759/cureus.30898
5. Гареева РР. Специфика симптоматики послеродового депрессивного расстройства у первородящих женщин. В: Наука – шаг в будущее: сборник материалов Всероссийской научно-практической конференции молодых ученых; 2025. Уфа: Уфимский университет науки и технологий; 2025. С. 128–135.
Gareeva RR. Spetsifika simptomatiki poslerodovogo depressivnogo rasstroystva u pervorodyashchikh zhenshchin. In: Nauka – shag v budushchee: proceedings of the All-Russian Scientific and Practical Conference of Young Scientists; 2025. Ufa: Ufa University of Science and Technology; 2025. p. 128–135. Russian.
https://www.elibrary.ru/item.asp?id=88825604
6. Zhao XH, Zhang ZH. Risk factors for postpartum depression: An evidence-based systematic review of systematic reviews and meta-analyses. Asian J Psychiatr. 2020;53:102353.
https://doi.org/10.1016/j.ajp.2020.102353
7. Amodeo G, Laurenzi PF, Santucci A, Cuomo A, Bolognesi S, Goracci A, Rossi R, Beccarini Crescenzi B, Neal SM, Fagiolini A. Advances in treatment for postpartum major depressive disorder. Expert Opin Pharmacother. 2020;21(14):1685-1698.
https://doi.org/10.1080/14656566.2020.1779702
8. Макарова М.А., Тихонова Ю.Г., Авдеева Т.И., Игнатко И.В., Кинкулькина М.А. Послеродовая депрессия: факторы риска развития, клинические и терапевтические аспекты. Неврология, нейропсихиатрия, психосоматика. 2021;13(4):75–80.
Makarova MA, Tikhonova YG, Avdeeva TI, Ignatko IV, Kinkulkina MA. Postpartum depression: risk factors for development, clinical and therapeutic aspects. Nevrologiya, Neyropsikhiatriya, Psikhosomatika = Neurology, neuropsychiatry, psychosomatics. 2021;13(4):75-80. Russian.
https://doi.org/10.14412/2074-2711-2021-4-75-80
9. Стрижаков А.Н., Игнатко И.В., Родионова А.М. Психоэмоциональный статус родильниц после естественного и абдоминального родоразрешения. Здоровье и образование в XXI веке. 2025;16(4):226.
Strizhakov AN, Ignatko IV, Rodionova AM. Psychoemotional status of parturients after natural and abdominal delivery. Zdorov'ye i obrazovaniye v XXI veke = Health and Education in the 21st Century. 2025;16(4):226. Russian.
10. Эдельханова А.И., Зубков Д.В., Скворцова А.В., Нурмухамбетова А.Н., Шайзадина А.А., Рымбек К.А. Связь между методом родоразрешения и послеродовой депрессией: обзор литературы. Репрод Мед (Центр Азия). 2024;2:88–94.
Edelkhanova AI, Zubkov DV, Skvortsova AV, Nurmukhambetova AN, Shaizadina AA, Rymbek KA. Association between the method of delivery and postpartum depression: A literature review. Reprod Med (Centr Asia). 2024;2:88-94. Russian.
https://doi.org/10.37800/RM.2.2024.88-94
11. Sun L, Wang S, Li XQ. Association between mode of delivery and postpartum depression: A systematic review and network meta-analysis. ANZJP. 2020;55(6):588-601.
https://doi.org/10.1177/0004867420954284
12. Xu H, Ding Y, Ma Y, Xin X, Zhang D. Cesarean section and risk of postpartum depression: A meta-analysis. J Psychosom Res. 2017;97:118-126.
https://doi.org/10.1016/j.jpsychores.2017.04.016
13. Cerra C, Morelli R, Di Mascio D, Buca D, Di Sebastiano F, Liberati M, di Sebastiano F, Liberati M, D'Antonio F. Maternal outcomes of cesarean delivery performed at early gestational ages: a systematic review and meta-analysis. Am J Obstet Gynecol MFM. 2021;3(4):100360.
https://doi.org/10.1016/j.ajogmf.2021.100360
14. Ning J, Deng J, Li S, Lu C, Zeng P. Meta-analysis of association between caesarean section and postpartum depression risk. Front Psychiatry. 2024;15:1361604.
https://doi.org/10.3389/fpsyt.2024.1361604
15. Марат Ұ.М., Лактионова М.В., Касенова М.А., Баймуратова М.А., Наханова Ж.К. Проблемы учета послеродовых психических расстройств (F53) в Казахстане: эпидемиологический и клинический анализ. Репрод Мед (Центр Азия). 2026;(2):153–162.
Marat UM, Laktionova MV, Kassenova MA, Baimuratova MA, Nakhanova ZhK. Problems in the registration of postpartum mental disorders (F53) in Kazakhstan: an epidemiological and clinical analysis. Reprod Med (Centr Asia). 2026;(2):153–162. Russian.
https://repromed.kz/index.php/journal/article/view/776
16. Li Y. Review of risk factors screening of postpartum depression and its interventions. Chin Gen Pract. 2020;23:266–71.
https://doi.org/10.12114/j.issn.1007-9572.2019.00.773
17. Smithson S, Mirocha J, Horgan R, Graebe R, Massaro R, Accortt E. Unplanned cesarean delivery is associated with risk for postpartum depressive symptoms in the immediate postpartum period. J Matern Fetal Neonatal Med. 2022;35:3860–6.
https://doi.org/10.1080/14767058.2020.1841163
18. Doke PP, Vaidya VM, Narula APS, Datar MC, Patil AV, Panchanadikar TM, et al. Assessment of difference in postpartum depression among caesarean and vaginally delivered women at 6-week follow-up in hospitals in Pune District, India: an observational cohort study. BMJ Open. 2021;11:e052008.
https://doi.org/10.1136/bmjopen-2021-052008
19. Liu TC, Peng HC, Chen C, Chen CS. Mode of delivery is associated with postpartum depression: do women with and without depression history exhibit a difference? Healthcare (Basel). 2022;10(7):1308.
https://doi.org/10.3390/healthcare10071308
20. Skov SK, Hjorth S, Kirkegaard H, Olsen J, Nohr EA. Mode of delivery and short-term maternal mental health: A follow-up study in the Danish national birth cohort. Int J Gynaecol Obstet. 2022;159:457–65.
https://doi.org/10.1002/ijgo.14155
21. Baba S, Ikehara S, Eshak ES, Ueda K, Kimura T, Iso H. Association between mode of delivery and postpartum depression: the Japan environment and children's study (Jecs). J Epidemiol. 2023;33(5):209–216.
https://doi.org/10.2188/jea.JE20210117
22. Dousti R, Hakimi S, Pourfathi H, Nourizadeh R, Sattarzadeh N. Cesarean section can be related with postpartum depression: A cross-sectional study. Int J Women’s Health Reprod Sci. 2022;10:219–24.
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