Impact of obesity on the incidence of complications in cesarean section
DOI:
https://doi.org/10.37800/RM.2.2026.693Keywords:
obesity, body mass index, cesarean section, intraoperative complications, postoperative complications, surgical site infection, thromboembolic complications, pregnancyAbstract
Relevance: Obesity among women of reproductive age is a growing public health challenge, including during pregnancy. Excess body weight increases the risk of obstetric and surgical complications, especially in cesarean deliveries. Although international data exist, the impact of obesity severity on intraoperative and postoperative complications in domestic practice remains understudied, highlighting the need for further research.
The study aimed to assess the impact of body mass index (BMI) on the frequency and nature of intraoperative, postoperative, and neonatal complications associated with cesarean section.
Materials and Methods: A retrospective cohort analysis of medical records from patients who underwent cesarean delivery at the obstetric hospitals in Shakhtinsk (Kazakhstan) from 2023 to 2025 was conducted. Patients were stratified according to the World Health Organization BMI classification. Intraoperative parameters, postoperative complications, and neonatal outcomes were evaluated. Statistical analysis included the chi-square test, t-test, ANOVA, correlation analysis, and calculation of relative risks.
Results: A significant increase in the frequency of intra- and postoperative complications was established as BMI increased. In patients with obesity, higher blood loss, increased duration of surgery, increased frequency of transition to general anesthesia, and organ trauma were noted. Postoperative infectious complications, seroma, endometritis, and thromboembolic events were significantly more common in grade II-III obesity. A positive correlation between BMI and the risk of postoperative wound infections and surgical duration was revealed. In addition, a worsening of neonatal outcomes in patients with high BMI was established: the frequency of macrosomia and respiratory disorders in newborns increased, as well as the frequency of admission to the neonatal intensive care unit. Grade II-III obesity significantly increased the risk of postoperative wound infection and long-term hospitalization.
Conclusion: Obesity is an independent risk factor for adverse cesarean section outcomes. Higher obesity severity increases surgical, anesthetic, and infectious complications, highlighting the need for individualized management and optimized preventive strategies.
References
1. Horwood G, Erwin E, Guo Y, Aston B, Souza SCS, Gaudet LM. Risk associated with planned mode of delivery in women with obesity: a large population-based retrospective cohort study. Int J Obes (Lond). 2025;49(5):835-843.
https://doi.org/10.1038/s41366-024-01709-x
2. Machado LSM. Cesarean section in morbidly obese parturients: Practical implications and complications. North Am J Med Sci. 2012;4(1):13-18.
https://doi.org/10.4103/1947-2714.92895
3. Alanis MC, Villers MS, Law TL, Steadman EM, Robinson CJ. Complications of cesarean delivery in the massively obese parturient. Am J Obstet Gynecol. 2010;203(3):271.e1-271.e7.
https://doi.org/10.1016/j.ajog.2010.06.049
4. Conner SN, Verticchio JC, Tuuli MG, Odibo AO, Macones GA, Cahill AG. Maternal obesity and risk of post-cesarean wound complications. Am J Perinatol. 2013;31(4):299-304.
https://doi.org/10.1055/s-0033-1348402
5. Weiss JL, Malone FD, Emig D, Ball RH, Nyberg DA, Comstock CH, Saade G, Eddleman K, Carter SM, Craigo SD, Carr SR, D'Alton ME, FASTER Research Consortium. Obesity, obstetric complications and cesarean delivery rate – A population-based screening study. Am J Obstet Gynecol. 2004;190(4):1091-1097.
https://doi.org/10.1016/j.ajog.2003.09.058
6. Kent L, McGirr M, Eastwood K-A. Global trends in prevalence of maternal overweight and obesity: A systematic review and meta-analysis of routinely collected data retrospective cohorts. Int J Popul Data Sci. 2024;9(2):2401.
https://doi.org/10.23889/ijpds.v9i2.2401
7. Bjorklund J, Wiberg-Itzel E, Wallstrom T. Is there an increased risk of cesarean section in obese women after induction of labor? A retrospective cohort study. PLoS ONE. 2022;17(2):e0263685.
https://doi.org/10.1371/journal.pone.0263685
8. Daida Y, Pedula K. Prevalence of overweight and obese prepregnancy BMI and excessive gestational weight gain using Asian-specific cutoffs among Asian and mixed-Asian women living in Hawaii: A retrospective cohort study. Matern Child Health J. 2022;27(4):728-736. https://doi.org/10.1007/s10995-022-03560-w
9. Тайжанова Д.Ж., Рустембеккызы Ж., Амирбекова Ж.Т., Комличенко Э.В., Понамарева О.А., Жанабаева С.У. Исходы беременности у женщин с предгестационным ожирением. Репродуктивная медицина. 2023;1(54):109-115.
Taizhanova DZh, Rustembekkyzy Zh, Amirbekova ZhT, Komlichenko EV, Ponomareva OA, Zhanabayeva SU. Pregnancy outcomes in women with pregestational obesity. Reproductive Medicine. 2023;1(54):109-115. Russian.
https://doi.org/10.37800/RM.1.2023.109-115
10. World Health organization. Obesity and overweight. 2024 [cited on Oct 15, 2025]. Available from:
https://www.who.int/news-room/fact-sheets/detail/obesity-and-overweight
11. Stupin JH, Arabin B. Overweight and obesity before, during and after pregnancy: Part 1: Pathophysiology, molecular biology and epigenetic consequences. Eur J Obstet Gynecol Reprod Biol. 2014;174(7):639-645.
https://doi.org/10.1055/s-0034-1368486
12. Lourenço J, Guedes-Martins L. Pathophysiology of maternal obesity and hypertension in pregnancy. J Cardiovasc Dev Dis. 2025;12(3):91.
https://doi.org/10.3390/jcdd12030091
13. Lopez-Jaramillo P, et al. Obesity and preeclampsia: Common pathophysiological mechanisms. Front Physiol. 2018;9:1838.
https://doi.org/10.3389/fphys.2018.01838
14. Azaïs H, Leroy A, Ghesquiere L, Deruelle P, Hanssens S. Effects of adipokines and obesity on uterine contractility. orCytokine Growth Factor Rev. 2017;34:59-66.
https://doi.org/10.1016/j.cytogfr.2017.01.001
15. Zoorob D, Zarudskaya O, Van Hook J, Moussa HN. Maternal morbidity associated with skin incision type at cesarean delivery in obese patients: a systematic review. Future Sci OA. 2020;7(3):FSO669.
https://doi.org/10.2144/fsoa-2020-0160
16. Mastrogiannis DS, Baranco N. Optimal skin incision techniques and perioperative considerations for cesarean delivery in super obese patients. J Obes Weight Loss Ther. 2024;S8:005.
https://doi.org/10.4172/2165-7904.S8-005
17. Lamon A, Habib A. Managing anesthesia for cesarean section in obese patients: current perspectives. Local Reg Anesth. 2016;9:45-57.
https://doi.org/10.2147/LRA.S64279
18. van den Bosch OFC, Fiset M-E, Downey K, Maxwell C, Carvalho JCA. Anesthetic management of patients with class 3 obesity undergoing elective cesarean delivery: a single-centre historical cohort study. Can J Anesth. 2023;70:202-210.
https://doi.org/10.1007/s12630-022-02365-3
19. Aimukhametova G, Ukybasova T, Hamidullina Z, Zhubanysheva K, Harun-or-Rashid M, Yoshida Y, Kasuya H, Sakamoto J. The impact of maternal obesity on mother and neonatal health: study in a tertiary hospital of Astana, Kazakhstan. Nagoya J Med Sci. 2012;74(1-2):83-92.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4831253/
20. Кесарево сечение: клинический протокол медицинского вмешательства [Internet]. Протокол № 180, одобрен Объединённой комиссией по качеству медицинских услуг Министерства здравоохранения Республики Казахстан, 17 марта 2023 г.; версия для Казахстана 2023. Алматы: MedElement; 2023 [дата доступа: 15.10.2025]. Адрес доступа:
Caesarean section: clinical protocol of medical intervention [Internet]. Protocol No. 180, approved by the Joint Commission on Quality of Medical Services of the Ministry of Health of the Republic of Kazakhstan, 17 Mar 2023; Kazakhstan version 2023. Almaty: MedElement; 2023 [cited Oct 15, 2025]. Russian. Available from:
https://diseases.medelement.com/disease/кесарево-сечение-кп-рк-2023/17600
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